SOCS3 Antikörper
(1 reference)-
- Target Alle SOCS3 Antikörper anzeigen
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser SOCS3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Spezifität
- The antibody SO1 reacts with SOCS3, an intracellular cytokine signaling inhibitor.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Full-length SOCS3 protein.
- Klon
- SO1
- Isotyp
- IgG2b
- Top Product
- Discover our top product SOCS3 Primärantikörper
-
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibody
SOCS3 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reaktivität: Human ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 155-225) antibodySOCS3 Reaktivität: Maus, Ratte ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-224) antibodySOCS3 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (C-Term) antibodySOCS3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-226) antibodySOCS3 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1E4 unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 71-85), (Middle Region) antibodySOCS3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 3 (SOCS3) (AA 1-225) antibodySOCS3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
-
- Applikationshinweise
- Western blotting: Positive control: HeLa human cervix carcinoma cell line, reducing conditions.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
-
-
: "Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion." in: Endocrine-related cancer, Vol. 14, Issue 4, pp. 1007-19, (2007) (PubMed).
-
: "Suppressor of cytokine signalling-3 is up-regulated by androgen in prostate cancer cell lines and inhibits androgen-mediated proliferation and secretion." in: Endocrine-related cancer, Vol. 14, Issue 4, pp. 1007-19, (2007) (PubMed).
-
- Target
- SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))
- Andere Bezeichnung
- SOCS3 (SOCS3 Produkte)
- Hintergrund
- Suppressor of cytokine signaling 3,SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.,SOCS-3, CIS3, SSI3
- Gen-ID
- 9021
- UniProt
- Q6FI39
- Pathways
- JAK-STAT Signalweg, Response to Growth Hormone Stimulus, Hepatitis C
-
