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Thyroglobulin Antikörper

TG Reaktivität: Human IHC (p) Wirt: Maus Monoclonal 2H11 unconjugated
Produktnummer ABIN94483
  • Target Alle Thyroglobulin (TG) Antikörper anzeigen
    Thyroglobulin (TG)
    Reaktivität
    • 101
    • 36
    • 36
    • 2
    • 1
    Human
    Wirt
    • 62
    • 39
    • 3
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 66
    • 41
    Monoklonal
    Konjugat
    • 67
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Thyroglobulin Antikörper ist unkonjugiert
    Applikation
    • 42
    • 40
    • 27
    • 25
    • 16
    • 15
    • 12
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    The antibody 2H11 recognizes thyroglobulin (TG), a 610 kDa extracellular secreted glycoprotein specific to the thyroid gland. TG is mainly expressed on thyroid follicular cells (99,1 %).
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    thyroid follicular cells
    Klon
    2H11
    Isotyp
    IgG1
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  • Applikationshinweise
    Immunohistochemistry (paraffin sections): Recommended dilution: 1:80 - 1:100, pretreatment: heat retrieval in 0.01M citrate buffer, pH 6 (microwave oven), positive tissue: thyroid gland, follicular adenoma.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Magro, Perissinotto, Schiappacassi, Goletz, Otto, Müller, Bisceglia, Brown, Ellis, Grasso, Colombatti, Perris: "Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas." in: The American journal of pathology, Vol. 163, Issue 1, pp. 183-96, (2003) (PubMed).

  • Target
    Thyroglobulin (TG)
    Andere Bezeichnung
    Thyroglobulin (TG Produkte)
    Hintergrund
    Thyroglobulin,Thyroid disorders are often associated with autoimmune diseases and thyroid cancer.,TG, TGN, AITD3
    Gen-ID
    7038
    UniProt
    P01266
    Pathways
    Thyroid Hormone Synthesis
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