Kinesin Antikörper (AA 331-906)

Produktnummer ABIN94498

Produktdetails anti-Kinesin Antikörper

Target: Kinesin

Bindungsspezifität: AA 331-906

Reaktivität: Human, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kinesin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Spezifität: The polyclonal antibody detects total level of endogenous kinesin protein (intracellular antigen).

Kreuzreaktivität (Details): Human, Mouse, Porcine, Other not tested

Aufreinigung: Purified by ligand affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: stalk domain of human kinesin (aa 331-906) expressed in E. coli (FKHC3)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-Kinesin Antikörper (ABIN94498)

Malcová-Janatová, Richterová, Dráber, Hasek: "Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains." in: Folia microbiologica, Vol. 49, Issue 6, pp. 665-70, (2005) (PubMed).

Details zu Kinesin

Target: Kinesin

Abstract: Kinesin Produkte

Synonyme: kinesin antikoerper, putative kinesin antikoerper, Tc00.1047053510323.120 antikoerper, Tc00.1047053508153.200 antikoerper, LmjF29.2390 antikoerper, LINJ_29_2500 antikoerper, LBRM_29_2360 antikoerper

Hintergrund: Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.,KIN