ARHGAP10 Antikörper (Middle Region)

Produktnummer ABIN950486

Produktdetails anti-ARHGAP10 Antikörper

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Bindungsspezifität: AA 240-267, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to ARHGAP10.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 240-267 amino acids from the Central region of human ARHGAP10

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ARHGAP10

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Andere Bezeichnung: ARHGAP10 / GRAF2 (ARHGAP10 Produkte)

Hintergrund: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).Synonyms: GTPase regulator associated with focal adhesion kinase 2, Graf-related protein 2, Rho GTPase-activating protein 10, Rho-type GTPase-activating protein 10

Gen-ID: 79658

NCBI Accession: NP_078881