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Axin Antikörper (C-Term)
AXIN1
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-Axin Antikörper
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Target
Alle Axin (AXIN1) Antikörper anzeigen
Axin (AXIN1)
(Axin 1 (AXIN1))
Bindungsspezifität
Alle Epitope für Axin Antikörper
AA 717-746, C-Term
Reaktivität
Alle Reaktivitäten für Axin Antikörper
Human
Wirt
Alle Wirte für Axin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Axin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Axin Antikörper
Dieser Axin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Axin Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody reacts to Axin-1.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 717-746 amino acids from the C-terminal region of human AXIN1
Isotyp
Ig Fraction
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Discover our top product AXIN1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) sodium azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu Axin
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Target
Axin (AXIN1)
(Axin 1 (AXIN1))
Andere Bezeichnung
Axin-1 (AXIN1 Produkte )
Synonyme
AXIN1 antikoerper, axin antikoerper, fused antikoerper, xAxin antikoerper, LOC100226467 antikoerper, AXIN antikoerper, PPP1R49 antikoerper, AI316800 antikoerper, Axin antikoerper, Fu antikoerper, Kb antikoerper, Ki antikoerper, kinky antikoerper, knobbly antikoerper, AXIN1-RGS antikoerper, wu:fi22e03 antikoerper, wu:fj14c08 antikoerper, wu:fk11b03 antikoerper, zgc:109872 antikoerper, axin 1 antikoerper, axin 1 S homeolog antikoerper, axin 1 L homeolog antikoerper, AXIN1 antikoerper, axin1.S antikoerper, axin1.L antikoerper, Axin1 antikoerper, axin1 antikoerper
Hintergrund
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: AXIN, AXIN1, Axis inhibition protein 1
Gen-ID
8312
NCBI Accession
NP_003493
Pathways
WNT Signalweg , Sensory Perception of Sound , Regulation of G-Protein Coupled Receptor Protein Signaling
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