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Angiopoietin 2 Antikörper (N-Term)

ANGPT2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN95113
  • Target Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigen
    Angiopoietin 2 (ANGPT2)
    Bindungsspezifität
    • 15
    • 10
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 72
    • 35
    • 26
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 74
    • 10
    • 4
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 67
    • 24
    Polyklonal
    Konjugat
    • 45
    • 10
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Angiopoietin 2 Antikörper ist unkonjugiert
    Applikation
    • 61
    • 31
    • 31
    • 13
    • 13
    • 11
    • 10
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    Western Blotting (WB)
    Spezifität
    This antiserum is directed against mouse angiopoietin-2 and shows no reactivity with angiopoietin-1 from mouse-derived proteins. A 75 kDa band is detected when assayed by immunoblot. This reagent cross-reacts with human angiopoietin-2. Partially cross-reactivity is noted with human angiopoietin-1.
    Produktmerkmale
    Anti Antiopoietin-2 Antibody recognizes Angiopoietin-2 (Ang-2) that has importance in development of the endothelium through regulation of tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding and thus blocks receptor phosphorylation. Ang-2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
    Sterilität
    Sterile filtered
    Immunogen
    This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide, corresponding to a region near the N-terminus of mouse angiopoietin-2 protein, conjugated to KLH using maleimide.
    Immunogen Type: Peptide
    Top Product
    Discover our top product ANGPT2 Primärantikörper
  • Applikationshinweise
    Angiopoietin 2 Antibody is suitable for western blotting and other antibody based assays. A 1:500 dilution is recommended for western blotting. The reaction of this antiserum directly with cell supernatants may result in high background due to reactivity of components in the serum. This can be alleviated by first immunoprecipitating the antibody:antigen complex and then detecting the antigen. This method results in a very clean, strong signal.
    Kommentare

    Gene Name: ANG-2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Haltbarkeit
    12 months
  • Câmpean, Karpe, Haas, Atalla, Peters, Rupprecht, Liebner, Acker, Plate, Amann: "Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1174-84, (2008) (PubMed).

    Davis, Aldrich, Jones, Acheson, Compton, Jain, Ryan, Bruno, Radziejewski, Maisonpierre, Yancopoulos: "Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning." in: Cell, Vol. 87, Issue 7, pp. 1161-9, (1997) (PubMed).

  • Target
    Angiopoietin 2 (ANGPT2)
    Andere Bezeichnung
    Angiopoietin 2 (ANGPT2 Produkte)
    Synonyme
    AGPT2 antikoerper, ANG2 antikoerper, Agpt2 antikoerper, Ang-2 antikoerper, Ang2 antikoerper, ang2 antikoerper, angpt2 antikoerper, ANGIOPOIETIN-2 antikoerper, ANG-2 antikoerper, ANGPT2 antikoerper, Angrp antikoerper, Rnase5b antikoerper, ANG3 antikoerper, C11orf2 antikoerper, C11orf3 antikoerper, FFR antikoerper, angiopoietin 2 antikoerper, angiopoietin 2b antikoerper, angiogenin, ribonuclease A family, member 2 antikoerper, VPS51, GARP complex subunit antikoerper, ANGPT2 antikoerper, Angpt2 antikoerper, angpt2b antikoerper, Ang2 antikoerper, VPS51 antikoerper
    Hintergrund
    Anti Antiopoietin-2 Antibody recognizes Angiopoietin-2 (Ang-2) that has importance in development of the endothelium through regulation of tyrosine phosphorylation of the membrane receptor Tie-2/Tek. Ang-1 binding to Tie-2/Tek causes phosphorylation of the receptor. Ang-2 competes for this binding and thus blocks receptor phosphorylation. Ang-2 expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
    Synonyms: AGPT 2 antibody, Agpt2 antibody, ANG 2 antibody, ANG2 antibody, Angiopoietin 2a antibody, Angiopoietin 2B antibody, Angiopoietin2 antibody, ANGPT 2 antibody, ANGPT2 antibody, Tie2 ligand antibody
    Gen-ID
    11601
    UniProt
    O35608
    Pathways
    RTK Signalweg
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