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Chromogranin A Antikörper (C-Term)

Name: Chromogranin A Antikörper (C-Term)
SKU: ABIN951517
Price: 830.31 EUR
Availability: InStock

CHGA Reaktivität: Human IF, FACS, WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

CMGA Antibody (C-term) western blot analysis in A549 cell line lysates (35µg/lane). (Chromogranin A Antikörper (C-Term))

CMGA Antibody (C-term) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram). (Chromogranin A Antikörper (C-Term))

FACS

Confocal immunofluorescent analysis of CMGA Antibody (C-term)(Cat#AP50981PU-N) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Chromogranin A Antikörper (C-Term))

CMGA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (Chromogranin A Antikörper (C-Term))

IHC (p)

4 Abbildungen

(1 reference)

Produktnummer ABIN951517

Datenblatt (PDF)

Target Alle Chromogranin A (CHGA) Antikörper anzeigen

Chromogranin A (CHGA)
Bindungsspezifität
20

15

7

6

5

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 383-412, C-Term
Reaktivität
207

76

66

29

28

15

6

5

4

3

2

2

1

1
Human
Wirt
117

98

5

1
Kaninchen
Passende Sekundärantikörper
Klonalität
124

96
Polyklonal
Konjugat
95

17

11

10

10

10

10

10

7

5

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Chromogranin A Antikörper ist unkonjugiert
Applikation
110

105

77

68

60

51

29

14

13

11

11

5

3

3

3

1

1

1

1

1

1
Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität

This antibody reacts to CMGA.

Kreuzreaktivität (Details)

Species reactivity (tested):Human.

Aufreinigung

Affinity chromatography on Protein A

Immunogen

KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of human CMGA

Isotyp

Ig Fraction

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.25 mg/mL

Buffer

PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Shi, Duan, Liu, Zhou, Liang: "Genetic alterations and protein expression in combined small cell lung cancers and small cell lung cancers arising from lung adenocarcinomas after therapy with tyrosine kinase inhibitors." in: Oncotarget, Vol. 7, Issue 23, pp. 34240-9, (2018) (PubMed).
Target

Chromogranin A (CHGA)

Andere Bezeichnung

Chromogranin A (CHGA Produkte)

Synonyme

CGA antikoerper, CG-ALPHA antikoerper, FSHA antikoerper, GPHA1 antikoerper, GPHa antikoerper, HCG antikoerper, LHA antikoerper, TSHA antikoerper, ChrA antikoerper, fj05f09 antikoerper, si:dkey-177p2.2 antikoerper, wu:fj05f09 antikoerper, zgc:101749 antikoerper, zgc:56075 antikoerper, CHGA antikoerper, cgA antikoerper, chga antikoerper, chromogranin A antikoerper, glycoprotein hormones, alpha polypeptide antikoerper, uncharacterized CHGA antikoerper, chromogranin A S homeolog antikoerper, CHGA antikoerper, CGA antikoerper, Chga antikoerper, chga antikoerper, chga.S antikoerper

Hintergrund

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.Synonyms: CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I

Molekulargewicht

50688 Da

Gen-ID

1113

NCBI Accession

NP_001266

Pathways

Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling