CLASP2 Antikörper (AA 1005-1034)

Produktnummer ABIN951541

Produktdetails anti-CLASP2 Antikörper

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Bindungsspezifität: AA 1005-1034

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLASP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human and Mouse.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 1005~1034 amino acids from the Y1019 region of human CLASP2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CLASP2

Target: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Andere Bezeichnung: CLASP2 (CLASP2 Produkte)

Synonyme: zgc:77279 antikoerper, DKFZp459M112 antikoerper, 1500004F14Rik antikoerper, 8030404L10Rik antikoerper, C77448 antikoerper, CLASP2beta antikoerper, mKIAA0627 antikoerper, cytoplasmic linker associated protein 2 antikoerper, CLIP associating protein 2 antikoerper, clasp2 antikoerper, CLASP2 antikoerper, Clasp2 antikoerper

Hintergrund: CLASP2 is microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.Synonyms: CLIP-associating protein 2, Cytoplasmic linker-associated protein 2, KIAA0627, Protein Orbit homolog 2, hOrbit2

Molekulargewicht: 141133 Da

Gen-ID: 9606

Pathways: Microtubule Dynamics, Maintenance of Protein Location