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COCH Antikörper (Middle Region)

COCH Reaktivität: Human WB, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN951612
  • Target Alle COCH Antikörper anzeigen
    COCH (Cochlin (COCH))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    AA 398-428, Middle Region
    Reaktivität
    • 48
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 46
    • 2
    Kaninchen
    Klonalität
    • 48
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COCH Antikörper ist unkonjugiert
    Applikation
    • 37
    • 27
    • 16
    • 12
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to COCH.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 398-428 amino acids from the Central region of human COCH
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product COCH Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    COCH (Cochlin (COCH))
    Andere Bezeichnung
    Cochlin (COCH Produkte)
    Synonyme
    AW122937 antikoerper, Coch-5B2 antikoerper, D12H14S564E antikoerper, COCH-5B2 antikoerper, COCH5B2 antikoerper, DFNA9 antikoerper, cochlin antikoerper, Coch antikoerper, COCH antikoerper
    Hintergrund
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94 % and 79 % amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq].Synonyms: COCH, COCH-5B2, COCH5B2
    Molekulargewicht
    59483 Da
    Gen-ID
    1690
    NCBI Accession
    NP_001128530
    Pathways
    Sensory Perception of Sound
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