DLL3 Antikörper (C-Term)

Produktnummer ABIN951924

Produktdetails anti-DLL3 Antikörper

Target: DLL3 (delta Like Protein 3 (DLL3))

Bindungsspezifität: AA 526-556, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes DLL3 at C-term .

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 526-556aa) of human DLL3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DLL3

Target: DLL3 (delta Like Protein 3 (DLL3))

Andere Bezeichnung: DLL3 (DLL3 Produkte)

Synonyme: SCDO1 antikoerper, pu antikoerper, pudgy antikoerper, delta like canonical Notch ligand 3 antikoerper, delta-like 3 (Drosophila) antikoerper, DLL3 antikoerper, Dll3 antikoerper

Hintergrund: Delta-like protein 3 is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.Synonyms: Delta-3, Delta-like protein 3

Gen-ID: 10683

NCBI Accession: NP_058637

Pathways: Notch Signalweg