Dynamitin Antikörper (Middle Region)

Produktnummer ABIN952005

Produktdetails anti-Dynamitin Antikörper

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Bindungsspezifität: AA 191-219, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human Dynactin subunit 2 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of Human Dynactin subunit 2. Genename: DCTN2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Dynamitin

Target: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Andere Bezeichnung: Dynactin Subunit 2 (DCTN2 Produkte)

Synonyme: DCTN2 antikoerper, dctn2 antikoerper, dctn50 antikoerper, dynamitin antikoerper, rbp50 antikoerper, CG8269 antikoerper, DMN antikoerper, Dmel\\CG8269 antikoerper, P50 antikoerper, dDyn antikoerper, dmn antikoerper, dyna antikoerper, l(2)k16109 antikoerper, l(2)k16218 antikoerper, p50 antikoerper, p50/Dmn antikoerper, p50/dynamitin antikoerper, 2310042E05Rik antikoerper, C130077D06Rik antikoerper, C87049 antikoerper, DCTN-50 antikoerper, GMP23-48K antikoerper, RBP50 antikoerper, DCTN50 antikoerper, DYNAMITIN antikoerper, zgc:63867 antikoerper, dynactin subunit 2 antikoerper, dynactin subunit 2 S homeolog antikoerper, Dynactin 2, p50 subunit antikoerper, dynactin 2 antikoerper, dynactin 2 (p50) antikoerper, dynactin subunit 2 L homeolog antikoerper, DCTN2 antikoerper, dctn2.S antikoerper, DCTN2-p50 antikoerper, dctn2 antikoerper, Dctn2 antikoerper, dctn2.L antikoerper

Hintergrund: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.Synonyms: 50 kDa dynein-associated polypeptide, DCTN2, DCTN50, Dynactin 2, Dynactin complex 50 kDa subunit, RBP50, p50 dynamitin

Molekulargewicht: 44231 Da

Gen-ID: 10540

NCBI Accession: NP_006391

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization