EMILIN2 Antikörper

Produktnummer ABIN952078

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch EMILIN2 in WB, IP und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EMILIN2 Antikörper (ABIN952078)

Target: EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser EMILIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Klon: 828B3B3

Produktdetails anti-EMILIN2 Antikörper

Spezifität: This antibody was selected for its ability to detect Human Emilin-2.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Recombinant protein gC1q domain of EMILIN-2.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Centrifuge vial prior to opening. Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for at least 6 months.

Haltbarkeit: 6 months

Details zu EMILIN2

Target: EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))

Andere Bezeichnung: EMILIN2

Hintergrund: Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.Synonyms: EMILIN-2, Elastin microfibril interface-located protein 2, Elastin microfibril interfacer 2, Protein FOAP-10

Gen-ID: 84034

NCBI Accession: NP_114437

UniProt: Q9BXX0