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FBXW7 Antikörper (AA 599-708)

FBXW7 Reaktivität: Human WB, IHC (p), EIA Wirt: Maus Monoclonal 3D1 unconjugated
Produktnummer ABIN952295
  • Target Alle FBXW7 Antikörper anzeigen
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 599-708
    Reaktivität
    • 63
    • 35
    • 32
    • 16
    • 15
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 52
    • 12
    Maus
    Klonalität
    • 55
    • 9
    Monoklonal
    Konjugat
    • 33
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser FBXW7 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 24
    • 15
    • 13
    • 13
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    Recognizes Fbxw7
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein A Chromatography
    Immunogen
    FBXW7 (NP_361014, 599 a.a. ~ 708 a.a) partial recombinant protein with GST tag.
    Klon
    3D1
    Isotyp
    IgG2a
    Top Product
    Discover our top product FBXW7 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS, pH 7.2
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    Andere Bezeichnung
    FBXW7 (FBXW7 Produkte)
    Synonyme
    cdc4 antikoerper, AGO antikoerper, CDC4 antikoerper, FBW6 antikoerper, FBW7 antikoerper, FBX30 antikoerper, FBXO30 antikoerper, FBXW6 antikoerper, SEL-10 antikoerper, SEL10 antikoerper, hAgo antikoerper, hCdc4 antikoerper, 1110001A17Rik antikoerper, Cdc4 antikoerper, Fbw7 antikoerper, Fbwd6 antikoerper, Fbx30 antikoerper, Fbxo30 antikoerper, Fbxw6 antikoerper, F-box and WD repeat domain containing 7 antikoerper, F-box and WD-40 domain protein 7 antikoerper, Fbxw7 antikoerper, FBXW7 antikoerper, fbxw7 antikoerper
    Hintergrund
    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.Synonyms: Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW7, FBX30, SEL-10, SEL10, hAgo, hCDC4
    Gen-ID
    55294
    NCBI Accession
    NP_001013433
    UniProt
    Q969H0
    Pathways
    Notch Signalweg, EGFR Signaling Pathway
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