FBXW7 Antikörper (AA 599-708)
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- Target Alle FBXW7 Antikörper anzeigen
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Bindungsspezifität
- AA 599-708
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FBXW7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- Recognizes Fbxw7
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Aufreinigung
- Protein A Chromatography
- Immunogen
- FBXW7 (NP_361014, 599 a.a. ~ 708 a.a) partial recombinant protein with GST tag.
- Klon
- 3D1
- Isotyp
- IgG2a
- Top Product
- Discover our top product FBXW7 Primärantikörper
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 408-707) antibodyFBXW7 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 Reaktivität: Human WB, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Drosophila melanogaster, Affe, Xenopus laevis, Hamster, Huhn, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 Reaktivität: Maus, Ratte, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
- Andere Bezeichnung
- FBXW7 (FBXW7 Produkte)
- Synonyme
- cdc4 antikoerper, AGO antikoerper, CDC4 antikoerper, FBW6 antikoerper, FBW7 antikoerper, FBX30 antikoerper, FBXO30 antikoerper, FBXW6 antikoerper, SEL-10 antikoerper, SEL10 antikoerper, hAgo antikoerper, hCdc4 antikoerper, 1110001A17Rik antikoerper, Cdc4 antikoerper, Fbw7 antikoerper, Fbwd6 antikoerper, Fbx30 antikoerper, Fbxo30 antikoerper, Fbxw6 antikoerper, F-box and WD repeat domain containing 7 antikoerper, F-box and WD-40 domain protein 7 antikoerper, Fbxw7 antikoerper, FBXW7 antikoerper, fbxw7 antikoerper
- Hintergrund
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.Synonyms: Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW7, FBX30, SEL-10, SEL10, hAgo, hCDC4
- Gen-ID
- 55294
- NCBI Accession
- NP_001013433
- UniProt
- Q969H0
- Pathways
- Notch Signalweg, EGFR Signaling Pathway
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