GCLC Antikörper (N-Term)
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- Target Alle GCLC Antikörper anzeigen
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
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Bindungsspezifität
- AA 6-34, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GCLC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human GCL / GLCLC (N-term).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of Human GCLC / GLCLC
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product GCLC Primärantikörper
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anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 528-637) antibody
GCLC Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3H1 unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 1-30), (N-Term) antibodyGCLC Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB31687 unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (N-Term) antibodyGCLC Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Hund, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 1-30) antibodyGCLC Reaktivität: Human WB, IHC, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (N-Term) antibodyGCLC Reaktivität: Human, Maus, Ratte, Schwein WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 437-637) antibodyGCLC Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 1-252) antibodyGCLC Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 435-636) antibodyGCLC Reaktivität: Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) antibodyGCLC Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (AA 435-636) antibodyGCLC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- Andere Bezeichnung
- GCLC / GLCLC (GCLC Produkte)
- Hintergrund
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.Synonyms: GCS heavy chain, GLCL, GLCLC, Gamma-ECS, Gamma-glutamylcysteine synthetase, Glutamate-cysteine ligase catalytic subunit
- Molekulargewicht
- 72766 Da
- Gen-ID
- 2729
- NCBI Accession
- NP_001184044
- Pathways
- Cell RedoxHomeostasis
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