GLIS2 Antikörper (Middle Region)
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- Target Alle GLIS2 Antikörper anzeigen
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
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Bindungsspezifität
- AA 172-202, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GLIS2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human GLIS2 (Center).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 172-202 amino acids from the Central region of Human GLIS2.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product GLIS2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))
- Andere Bezeichnung
- GLIS2 (GLIS2 Produkte)
- Synonyme
- glis2b antikoerper, nkl-A antikoerper, xNKLb antikoerper, NKL antikoerper, NPHP7 antikoerper, Gli5 antikoerper, Klf16 antikoerper, Nkl antikoerper, glis2a antikoerper, nphp7 antikoerper, GLIS family zinc finger 2 L homeolog antikoerper, GLIS family zinc finger 2 antikoerper, GLIS family zinc finger 2 S homeolog antikoerper, glis2.L antikoerper, GLIS2 antikoerper, Glis2 antikoerper, glis2.S antikoerper
- Hintergrund
- This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.Synonyms: GLI-similar 2, NKL, Neuronal Krueppel-like protein, Zinc finger protein GLIS2
- Molekulargewicht
- 55689 Da
- Gen-ID
- 84662
- NCBI Accession
- NP_115964
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