GLRB Antikörper (N-Term)

Produktnummer ABIN952548

Produktdetails anti-GLRB Antikörper

Target: GLRB (Glycine Receptor, beta (GLRB))

Bindungsspezifität: AA 102-132, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse Glycine receptor beta (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 102-132 amino acids from the N-terminal region of Human Glycine receptor beta Genename: GLRB

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Andere Bezeichnung: Glycine Receptor beta (GLRB Produkte)

Synonyme: HKPX2 antikoerper, glrb antikoerper, MGC145156 antikoerper, AI853901 antikoerper, Glyrb antikoerper, spa antikoerper, spastic antikoerper, glrb2 antikoerper, zgc:101041 antikoerper, glycine receptor beta antikoerper, glycine receptor, beta antikoerper, glycine receptor, beta subunit antikoerper, glycine receptor, beta b antikoerper, GLRB antikoerper, Glrb antikoerper, glrb antikoerper, glrbb antikoerper

Hintergrund: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.Synonyms: GLRB, Glycine receptor 58 kDa subunit

Molekulargewicht: 56122 Da

Gen-ID: 2743

NCBI Accession: NP_000815