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IREB2 Antikörper (Middle Region)

IREB2 Reaktivität: Human WB, IHC (p), FACS, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN952944
  • Target Alle IREB2 Antikörper anzeigen
    IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
    Bindungsspezifität
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 208-238, Middle Region
    Reaktivität
    • 35
    • 13
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 5
    • 1
    Kaninchen
    Klonalität
    • 35
    • 3
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IREB2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 17
    • 12
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes Human IREB2 (Center).
    Aufreinigung
    Protein A column, followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 208-238 amino acids from the Central region of human IREB2
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product IREB2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
    Andere Bezeichnung
    IREB2 (IREB2 Produkte)
    Hintergrund
    IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.Synonyms: IRE-BP2, IRP2, Iron regulatory protein 2, Iron-responsive element-binding protein 2
    Molekulargewicht
    105045 Da
    Gen-ID
    3658
    NCBI Accession
    NP_004127
    Pathways
    Transition Metal Ion Homeostasis
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