IREB2 Antikörper (Middle Region)
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- Target Alle IREB2 Antikörper anzeigen
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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Bindungsspezifität
- AA 208-238, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IREB2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human IREB2 (Center).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 208-238 amino acids from the Central region of human IREB2
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IREB2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
- Andere Bezeichnung
- IREB2 (IREB2 Produkte)
- Hintergrund
- IREB2 is a RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.Synonyms: IRE-BP2, IRP2, Iron regulatory protein 2, Iron-responsive element-binding protein 2
- Molekulargewicht
- 105045 Da
- Gen-ID
- 3658
- NCBI Accession
- NP_004127
- Pathways
- Transition Metal Ion Homeostasis
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