ISL1 Antikörper (Middle Region)
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- Target Alle ISL1 Antikörper anzeigen
- ISL1 (ISL LIM Homeobox 1 (ISL1))
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Bindungsspezifität
- AA 155-185, Middle Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ISL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human and Mouse Islet-1 / ISL1 (Center).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 155-185 amino acids from the Central region of human Islet-1 / ISL1
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ISL1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- ISL1 (ISL LIM Homeobox 1 (ISL1))
- Andere Bezeichnung
- Islet-1 / ISL1 (ISL1 Produkte)
- Synonyme
- Xisl-1 antikoerper, Xislet-1 antikoerper, islet1 antikoerper, ISLET-1 antikoerper, ISLET1 antikoerper, Isl-1 antikoerper, islet-1 antikoerper, isl-1=homeobox antikoerper, Islet-1 antikoerper, ISL LIM homeobox 1 S homeolog antikoerper, ISL LIM homeobox 1 antikoerper, ISL1 transcription factor, LIM/homeodomain antikoerper, isl1.S antikoerper, ISL1 antikoerper, Isl1 antikoerper, isl1 antikoerper
- Hintergrund
- ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.Synonyms: Insulin gene enhancer protein ISL-1
- Molekulargewicht
- 39036 Da
- Gen-ID
- 3670
- NCBI Accession
- NP_002193
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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