KDM4B Antikörper (C-Term)

Produktnummer ABIN952974

Produktdetails anti-KDM4B Antikörper

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Bindungsspezifität: AA 287-316, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse JMJD2B (Thr305)

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 287~316 amino acids from the C-terminal region of human JMJD2B

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-KDM4B Antikörper (ABIN952974)

Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

Details zu KDM4B

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Andere Bezeichnung: JMJD2B / KDM4B (KDM4B Produkte)

Synonyme: KDM4B antikoerper, JMJD2B antikoerper, jmjd2b antikoerper, si:ch211-124a3.4 antikoerper, TDRD14B antikoerper, 4732474L06Rik antikoerper, Jmjd2b antikoerper, mKIAA0876 antikoerper, lysine demethylase 4B antikoerper, lysine (K)-specific demethylase 4B antikoerper, KDM4B antikoerper, kdm4b antikoerper, Kdm4b antikoerper

Hintergrund: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.Synonyms: JHDM3B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KIAA0876, Lysine-specific demethylase 4B

Molekulargewicht: 121897 Da

Gen-ID: 23030

NCBI Accession: NP_055830

Pathways: Warburg Effekt