LFNG Antikörper (Middle Region)

Produktnummer ABIN953163

Produktdetails anti-LFNG Antikörper

Target: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Bindungsspezifität: AA 93-122, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LFNG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody recognizes Human LFNG (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 93~122 amino acids from the Central region of human LFNG

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LFNG

Target: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Andere Bezeichnung: LFNG (LFNG Produkte)

Synonyme: SCDO3 antikoerper, AW061165 antikoerper, id:ibd2614 antikoerper, id:ibd5029 antikoerper, id:ibd5138 antikoerper, l-fng antikoerper, wu:fc69h02 antikoerper, wu:fi34c01 antikoerper, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antikoerper, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog antikoerper, LFNG antikoerper, Lfng antikoerper, lfng.S antikoerper, lfng antikoerper

Hintergrund: LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).Synonyms: 3-N-acetylglucosaminyltransferase lunatic fringe, Beta-1, EC=2.4.1.222, LFNG, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Molekulargewicht: 41773 Da

Gen-ID: 3955

NCBI Accession: NP_001035257

Pathways: Notch Signalweg