LIN7C Antikörper (C-Term)

Produktnummer ABIN953176

Produktdetails anti-LIN7C Antikörper

Target: LIN7C (Lin-7 Homolog C (LIN7C))

Bindungsspezifität: AA 175-197, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIN7C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human LIN7C (C-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 175-197 amino acids from the C-terminal region of Human LIN7C.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu LIN7C

Target: LIN7C (Lin-7 Homolog C (LIN7C))

Andere Bezeichnung: LIN7C (LIN7C Produkte)

Synonyme: LIN7C antikoerper, fb75b09 antikoerper, wu:fb75b09 antikoerper, zgc:101881 antikoerper, LIN-7-C antikoerper, LIN-7C antikoerper, MALS-3 antikoerper, MALS3 antikoerper, VELI3 antikoerper, 9130007B12Rik antikoerper, AI303698 antikoerper, AU019331 antikoerper, AW125731 antikoerper, D2Ertd520e antikoerper, Veli3 antikoerper, lin-7 homolog C, crumbs cell polarity complex component antikoerper, lin-7 homolog C L homeolog antikoerper, lin-7 homolog C (C. elegans) antikoerper, LIN7C antikoerper, lin7c.L antikoerper, lin7c antikoerper, Lin7c antikoerper

Hintergrund: LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.Synonyms: LIN7C, Lin-7 homolog C, Lin-7C, MALS-3, MALS3, Mammalian lin-seven protein 3, VELI3, Veli-3 protein, Vertebrate lin-7 homolog 3

Molekulargewicht: 21834 Da

Gen-ID: 55327

NCBI Accession: NP_060832

Pathways: Synaptic Membrane