MOB1A Antikörper (N-Term)
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- Target Alle MOB1A (MOBKL1B) Antikörper anzeigen
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
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Bindungsspezifität
- AA 4-33, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MOB1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human MOBKL1B (N-term).
- Aufreinigung
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of Human MOBKL1B
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MOBKL1B Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
- Andere Bezeichnung
- MOBKL1B (MOBKL1B Produkte)
- Synonyme
- mob1 antikoerper, mob4b antikoerper, MOB1A antikoerper, MOBK1B antikoerper, MOB1 antikoerper, mats1 antikoerper, mobk1b antikoerper, mobkl1b antikoerper, MOBKL1B antikoerper, wu:fv69d04 antikoerper, zgc:56189 antikoerper, C2orf6 antikoerper, MATS1 antikoerper, Mob4B antikoerper, 4022402H07Rik antikoerper, MOB4B antikoerper, Mobk1b antikoerper, Mobkl1b antikoerper, MOB kinase activator 1A L homeolog antikoerper, MOB kinase activator 1A antikoerper, MOB kinase activator 1A pseudogene antikoerper, mob1a.L antikoerper, MOB1A antikoerper, mob1a antikoerper, LOC712156 antikoerper, Mob1a antikoerper
- Hintergrund
- Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.Synonyms: C2orf6, MOB4B, MOBK1B, Mob1 alpha, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, Protein Mob4B
- Molekulargewicht
- 25080 Da
- Gen-ID
- 55233
- NCBI Accession
- NP_060691
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