MBP Antikörper
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- Target Alle MBP Antikörper anzeigen
- MBP (Myelin Basic Protein (MBP))
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Reaktivität
- Human, Maus, Ratte
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Wirt
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Huhn
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Klonalität
- Polyklonal
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Konjugat
- Dieser MBP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Spezifität
- Specific for the ~18k & 22k myelin basic protein in Western blots of Rat brain homogenate.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Bovine, Mouse and Rat.
- Aufreinigung
- Ig Fraction
- Immunogen
- Three peptide sequences conserved in higher vertebrate MBP proteins.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product MBP Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at -20 °C.
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- Target
- MBP (Myelin Basic Protein (MBP))
- Andere Bezeichnung
- Myelin Basic Protein (MBP Produkte)
- Synonyme
- C76307 antikoerper, Hmbpr antikoerper, R75289 antikoerper, golli-mbp antikoerper, mld antikoerper, shi antikoerper, Mbps antikoerper, cb274 antikoerper, fj33b11 antikoerper, mbp antikoerper, wu:fj33b11 antikoerper, wu:fq15b02 antikoerper, zgc:136630 antikoerper, MGC115135 antikoerper, myelin basic protein antikoerper, myelin basic protein a antikoerper, myelin basic protein L homeolog antikoerper, MBP antikoerper, Mbp antikoerper, mbpa antikoerper, mbp antikoerper, mbp.L antikoerper
- Hintergrund
- Myelin Basic Protein (MBP) is one of the major proteins of the myelin sheath surrounding axons in the nervous system. Since it is of relatively low molecular weight and high abundance the protein sequence was determined from purified protein over 30 years ago (Eylar et al., 1971). The protein is made by oligodendrocytes in the central nervous system, so antibodies to MBP are good markers of this cell type. However, transcripts from the same gene are also expressed in certain hematopoetic lineage cells (Marty et al., 2002). In the central nervous system there are there different forms of the protein made by alternate transcription from a single gene, which have molecular weights of 21.5, 18.5, and 17.2 kDa. Since the two lower molecular weight forms are very close in molecular size, MBP antibodies typically show two bands on Western blots, one at about 22 kDa and another at about 18 kDa.Synonyms: MBP, Myelin membrane encephalitogenic protein
- Gen-ID
- 4155
- NCBI Accession
- NP_001020252
- UniProt
- P02686
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