WHSC2 Antikörper (Middle Region)
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- Target Alle WHSC2 Antikörper anzeigen
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
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Bindungsspezifität
- AA 261-290, Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WHSC2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects NELF-A (Center).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein A column followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 261-290 amino acids from the Central region of human WHSC2
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product WHSC2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- Target
- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
- Andere Bezeichnung
- NELF-A (WHSC2 Produkte)
- Synonyme
- BcDNA:SD07139 antikoerper, CG5874 antikoerper, Dmel\\CG5874 antikoerper, NELF antikoerper, NELF-A antikoerper, Whsc2 antikoerper, fi75f03 antikoerper, whsc2 antikoerper, wu:fi75f03 antikoerper, MGC85474 antikoerper, WHSC2 antikoerper, nelfa antikoerper, nelf-a antikoerper, p/okcl.15 antikoerper, Whsc2h antikoerper, Negative elongation factor A antikoerper, negative elongation factor complex member A antikoerper, negative elongation factor complex member A L homeolog antikoerper, negative elongation factor complex member A, Whsc2 antikoerper, Nelf-A antikoerper, Nelfa antikoerper, nelfa antikoerper, nelfa.L antikoerper, NELFA antikoerper
- Hintergrund
- This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.Synonyms: NELFA, Negative elongation factor A, P/OKcl.15, WHSC2
- Gen-ID
- 7469
- NCBI Accession
- NP_005654
- Pathways
- Chromatin Binding
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