Nibrin Antikörper (C-Term)
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- Target Alle Nibrin (NBN) Antikörper anzeigen
- Nibrin (NBN)
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Bindungsspezifität
- AA 609-638, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Nibrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human Nibrin (C-term).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 609-638 amino acids from the C-terminal region of Human Nibrin Genename: NBN
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NBN Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Nibrin (NBN)
- Andere Bezeichnung
- Nibrin (NBN Produkte)
- Synonyme
- NBN antikoerper, AT-V1 antikoerper, AT-V2 antikoerper, ATV antikoerper, NBS antikoerper, NBS1 antikoerper, P95 antikoerper, Nbs1 antikoerper, im:6911679 antikoerper, zgc:194152 antikoerper, nibrin antikoerper, NBN antikoerper, nbn antikoerper, Nbn antikoerper
- Hintergrund
- Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.Synonyms: Cell cycle regulatory protein p95, NBN, NBS, NBS1, Nijmegen breakage syndrome protein 1, P95
- Molekulargewicht
- 84959 Da
- Gen-ID
- 4683
- NCBI Accession
- NP_002476
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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