PAIP2 Antikörper (N-Term)

Produktnummer ABIN953979

Produktdetails anti-PAIP2 Antikörper

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Bindungsspezifität: AA 6-34, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human PAIP2 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PAIP2

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PAIP2

Target: PAIP2 (Poly Binding Protein Interacting Protein 2 (PAIP2))

Andere Bezeichnung: PAIP2 (PAIP2 Produkte)

Synonyme: PAIP2A antikoerper, DKFZp469O1314 antikoerper, 2310050K10Rik antikoerper, AU045972 antikoerper, paip2 antikoerper, poly(A) binding protein interacting protein 2 antikoerper, polyadenylate-binding protein-interacting protein 2 antikoerper, poly(A) binding protein interacting protein 2B L homeolog antikoerper, PAIP2 antikoerper, Paip2 antikoerper, paip2b.L antikoerper

Hintergrund: PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.Synonyms: PABP-interacting protein 2, PAIP-2, PAIP2A, Poly(A)-binding protein-interacting protein 2, Polyadenylate-binding protein-interacting protein 2

Molekulargewicht: 14984 Da

Gen-ID: 51247

NCBI Accession: NP_001028284