PAK6 Antikörper (Middle Region)

Produktnummer ABIN953980

Produktdetails anti-PAK6 Antikörper

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Bindungsspezifität: AA 275-305, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human PAK6 (Center).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 275-305 amino acids from the Central region of human PAK6

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: PAK6 (PAK6 Produkte)

Synonyme: PAK5 antikoerper, 4732456M09 antikoerper, pak6 antikoerper, si:ch211-158b22.3 antikoerper, p21 (RAC1) activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6 antikoerper, p21 protein (Cdc42/Rac)-activated kinase 6b antikoerper, PAK6 antikoerper, Pak6 antikoerper, pak6b antikoerper

Hintergrund: This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6

Molekulargewicht: 74869 Da

Gen-ID: 56924

NCBI Accession: NP_001122100