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C10orf2 Antikörper (C-Term)

C10ORF2 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN954086
  • Target Alle C10orf2 (C10ORF2) Antikörper anzeigen
    C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
    Bindungsspezifität
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 663-684, C-Term
    Reaktivität
    • 37
    • 14
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 36
    • 2
    Kaninchen
    Klonalität
    • 36
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser C10orf2 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 14
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to PEO1.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 663-684 amino acids from the C-terminal region of human C10orf2
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product C10ORF2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) sodium azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
    Andere Bezeichnung
    PEO1 / Twinkle (C10ORF2 Produkte)
    Hintergrund
    This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Synonyms: C10orf2, Progressive external ophthalmoplegia 1 protein, T7-like mitochondrial DNA helicase, Twinkle protein mitochondrial
    Gen-ID
    56652
    NCBI Accession
    NP_001157284
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