Phospholipase C delta 3 Antikörper (N-Term)

Produktnummer ABIN954186

Produktdetails anti-Phospholipase C delta 3 Antikörper

Target: Phospholipase C delta 3 (PLCd3)

Bindungsspezifität: AA 59-89, N-Term

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C delta 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human and Mouse PLCD3 (N-term).

Aufreinigung: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 59-89 amino acids from the N-terminal region of human PLCD3

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Phospholipase C delta 3

Target: Phospholipase C delta 3 (PLCd3)

Andere Bezeichnung: PLCD3 (PLCd3 Produkte)

Synonyme: 2610205J15Rik antikoerper, mKIAA1964 antikoerper, phospholipase C delta 3 antikoerper, phospholipase C, delta 3 antikoerper, PLCD3 antikoerper, Plcd3 antikoerper

Hintergrund: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq].Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-3, PLC-delta-3, Phospholipase C delta 3, Phospholipase C-delta-3

Molekulargewicht: 89258 Da

Gen-ID: 113026

NCBI Accession: NP_588614

Pathways: WNT Signalweg