Prothrombin Antikörper (Biotin)
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- Target Alle Prothrombin (F2) Antikörper anzeigen
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Prothrombin Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody is specific for Human Prothrombin (CaPro-20).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human.
- Immunogen
- Human Prothrombin (CaPro-20) purified from plasma.
- Klon
- CaPro-20
- Isotyp
- IgG1
- Top Product
- Discover our top product F2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Andere Bezeichnung
- Prothrombin (F2) (F2 Produkte)
- Synonyme
- PT antikoerper, RPRGL2 antikoerper, THPH1 antikoerper, Cf-2 antikoerper, Cf2 antikoerper, FII antikoerper, thrombin antikoerper, zgc:66319 antikoerper, wu:fb57c10 antikoerper, wu:fd42e09 antikoerper, wu:fd59d01 antikoerper, prothrombin antikoerper, F2 antikoerper, coagulation factor II, thrombin antikoerper, coagulation factor II antikoerper, coagulation factor II (thrombin) antikoerper, F2 antikoerper, f2 antikoerper
- Hintergrund
- Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia. Prothrombin is a 72 kDa blood clotting glycoprotein formed by and stored in the Liver. Prothrombin is present in the blood plasma and is converted to the key blood clotting agent thrombin, when blood vessels are damaged. Factor VII, another important haemostasis protein can be converted to VIIa by Factor IXa or Thrombin.Synonyms: Coagulation factor II
- Gen-ID
- 2147
- NCBI Accession
- NP_000497
- UniProt
- P00734
- Pathways
- Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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