Importin 11 Antikörper (C-Term)
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- Target Alle Importin 11 (IPO11) Antikörper anzeigen
- Importin 11 (IPO11)
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Bindungsspezifität
- AA 906-970, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Importin 11 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody recognizes Human RanBP11 / Importin-11 (C-term).
- Aufreinigung
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 906~970 amino acids from the C-terminal region of Human RanBP11 / Importin-11 Genename: IPO11
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product IPO11 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Importin 11 (IPO11)
- Andere Bezeichnung
- RanBP11 / Importin-11 (IPO11 Produkte)
- Synonyme
- MGC83107 antikoerper, IPO11 antikoerper, slrn antikoerper, ranbp11 antikoerper, RanBP11 antikoerper, 1700081H05Rik antikoerper, 2510001A17Rik antikoerper, AI314624 antikoerper, AW555235 antikoerper, E330021B14Rik antikoerper, Ranbp11 antikoerper, importin 11 S homeolog antikoerper, importin 11 antikoerper, importin-11 antikoerper, ipo11.S antikoerper, ipo11 antikoerper, IPO11 antikoerper, AFUA_1G03590 antikoerper, BDBG_04626 antikoerper, LOC100162908 antikoerper, Ipo11 antikoerper
- Hintergrund
- IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).Synonyms: IPO11, Imp11, Ran-binding protein 11
- Molekulargewicht
- 112535 Da
- Gen-ID
- 51194
- NCBI Accession
- NP_001128251
- Pathways
- Protein targeting to Nucleus
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