RBBP7 Antikörper (Middle Region)

Produktnummer ABIN954472

Produktdetails anti-RBBP7 Antikörper

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Bindungsspezifität: AA 190-219, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBBP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human RBBP7 (Center).

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 190-219 amino acids from the Central region of Human RBBP7. Genename: RBBP7

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RBBP7

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Andere Bezeichnung: RBBP7 / RBAP46 (RBBP7 Produkte)

Hintergrund: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: Histone-binding protein RBBP7, Nucleosome-remodeling factor subunit RBAP46, RBBP-7, Retinoblastoma-binding protein 7, Retinoblastoma-binding protein p46

Molekulargewicht: 47820 Da

Gen-ID: 5931

NCBI Accession: NP_002884