SLX5 antikoerper, SNURF antikoerper, AU018689 antikoerper, Gtrgeo8 antikoerper, ring finger protein 4 antikoerper, RNF4 antikoerper, Rnf4 antikoerper
Hintergrund
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.Synonyms: E3 ubiquitin ligase RNF4, RES4-26, Ring finger protein 4, SNURF