RNF4 Antikörper (C-Term)

Produktnummer ABIN954575

Produktdetails anti-RNF4 Antikörper

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Bindungsspezifität: AA 94-123, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes Human RNF4. Other species not tested.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 94-123 amino acids from the C-terminal region of human RNF4

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RNF4

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Andere Bezeichnung: RNF4 (RNF4 Produkte)

Hintergrund: The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.Synonyms: E3 ubiquitin ligase RNF4, RES4-26, Ring finger protein 4, SNURF

Molekulargewicht: 21319 Da

Gen-ID: 6047

NCBI Accession: NP_001171938

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway