SLAMF6 antikoerper, CD352 antikoerper, KALI antikoerper, KALIb antikoerper, Ly108 antikoerper, NTB-A antikoerper, NTBA antikoerper, SF2000 antikoerper, KAL1 antikoerper, KAL1b antikoerper, RGD1561848 antikoerper, SLAM family member 6 antikoerper, SLAMF6 antikoerper, Slamf6 antikoerper
Hintergrund
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.Synonyms: Activating NK receptor, KALI, LY108, NK-T-B-antigen, NTB-A