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TRADD Antikörper (Middle Region)
TRADD
Reaktivität: Human
WB, IF, IHC (p), FACS, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-TRADD Antikörper
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Target
Alle TRADD Antikörper anzeigen
TRADD
(TNFRSF1A-Associated Via Death Domain (TRADD))
Bindungsspezifität
Alle Epitope für TRADD Antikörper
AA 133-159, Middle Region
Reaktivität
Alle Reaktivitäten für TRADD Antikörper
Human
Wirt
Alle Wirte für TRADD Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TRADD Antikörper
Polyklonal
Konjugat
Alle Konjugate für TRADD Antikörper
Dieser TRADD Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TRADD Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
Spezifität
This antibody detects TRADD (Center).
Kreuzreaktivität (Details)
Species reactivity (tested):Human
Aufreinigung
Protein A column followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 133-159 amino acids from the Central region of human TRADD
Isotyp
Ig Fraction
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Details zu TRADD
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Target
TRADD
(TNFRSF1A-Associated Via Death Domain (TRADD))
Andere Bezeichnung
TRADD (TRADD Produkte )
Hintergrund
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].Synonyms: TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tumor necrosis factor receptor type 1-associated DEATH domain protein
Gen-ID
8717
NCBI Accession
NP_003780
Pathways
NF-kappaB Signalweg , Apoptose , Caspase Kaskade in der Apoptose , Positive Regulation of Endopeptidase Activity , Hepatitis C
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