UGDH Antikörper (C-Term)
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- Target Alle UGDH Antikörper anzeigen
- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
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Bindungsspezifität
- AA 464-494, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser UGDH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects UGDH (C-term).
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein A column followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide between 464-494 amino acids from the C-terminal region of human UGDH
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product UGDH Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
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- Target
- UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))
- Andere Bezeichnung
- UGDH (UGDH Produkte)
- Hintergrund
- The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.Synonyms: UDP-Glc dehydrogenase, UDP-GlcDH, UDP-glucose 6-dehydrogenase, UDPGDH
- Gen-ID
- 7358
- NCBI Accession
- NP_001171629
- Pathways
- Glycosaminoglycan Metabolic Process
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