Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PYM Antikörper (N-Term)

WIBG Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN955577
  • Target Alle PYM (WIBG) Antikörper anzeigen
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    AA 15-44, N-Term
    Reaktivität
    • 29
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 27
    • 2
    Kaninchen
    Klonalität
    • 27
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PYM Antikörper ist unkonjugiert
    Applikation
    • 21
    • 15
    • 13
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects WIBG / PYM (N-term).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Protein A column followed by peptide affinity purification
    Immunogen
    KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human WIBG
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product WIBG Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
  • Target
    PYM (WIBG) (Partner of Y14 and mago (WIBG))
    Andere Bezeichnung
    WIBG / PYM (WIBG Produkte)
    Synonyme
    BEST:HL05757 antikoerper, CG10330 antikoerper, CG30176 antikoerper, Dmel\\CG30176 antikoerper, PYM antikoerper, Pym antikoerper, UD3 antikoerper, A030010B05Rik antikoerper, zgc:65891 antikoerper, zgc:77281 antikoerper, Partner of Y14 and Mago antikoerper, Wibg protein antikoerper, PYM homolog 1, exon junction complex associated factor L homeolog antikoerper, PYM homolog 1, exon junction complex associated factor antikoerper, Pym antikoerper, wibg antikoerper, pym1.L antikoerper, PYM1 antikoerper, Pym1 antikoerper, pym1 antikoerper
    Hintergrund
    Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA, the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.Synonyms: Partner of Y14 and mago, Protein wibg homolog
    Gen-ID
    84305
    NCBI Accession
    NP_001137325
Sie sind hier:
Kundenservice