HCV 1b NS5B Antikörper (AA 111-130)

Produktnummer ABIN956403

Produktdetails anti-HCV 1b NS5B Antikörper

Target: HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))

Bindungsspezifität: AA 111-130

Reaktivität: Hepatitis C Virus (HCV)

Wirt: CHO Cells

Klonalität: Monoklonal

Konjugat: Dieser HCV 1b NS5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Sequenz: LSSKAVNHIR SVWKDLLEDT

Spezifität: Human, HCV subtype 1b NS5B

Produktmerkmale: Partially humanized, chimeric recombinant monoclonal

Aufreinigung: purifiedby protein G affinity chromatography

Immunogen: Recombinant Hepatitis C Virus subtype 1b nonstructuralprotein 5B (NS5B) RNA-dependent RNA polymerase (RdRp)

Klon: 9A2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISAtiter 1:1000, Western immunoblotting, reduced conditions, dilution 1:1000, Immunofluorescense 1:1000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml

Buffer: PBS pH 7.4, with 0.1%

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.

Lagerung: -20 °C

Informationen zur Lagerung: This product isshipped in non-frozen liquid form in ambient conditions

Details zu HCV 1b NS5B

Target: HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))

Abstract: HCV NS5b Produkte

Substanzklasse: Viral Protein

Hintergrund: Non-structural protein 5B (NS5B)represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, whichis a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronichepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunitRNA-dependent RNA polymerase is absolutely essential for the viral replication.Antibodyis derived from mouse anti-HCV NS5B monoclonal antoibody 9A2 expressing mousehybridoma culture. cDNA of antibody variable regions were isolated and clonedinto the human IgG1 constant region-containing antibody expression vector.Partially humanized, chimeric antibody was expressed by QMCF CHOEBNALT85 cellline. Antibody is used for high-specific efficient detection of soluble ormembrane-bound proteins fused with 9A2 epitope-tag sequence. For moreinformation please visit: http://icosagen.com/cell-based-assay/qmcf-assay-overview

UniProt: Q9WMX2