Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CASZ1 Antikörper (Internal Region)

Rockland 600-401-b62 CASZ1 Reaktivität: Human WB, ELISA, IHC, FM Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN964598
Hersteller Produkt- Nr.: 600-401-b62
  • Target Alle CASZ1 Antikörper anzeigen
    CASZ1 (Castor Zinc Finger 1 (CASZ1))
    Bindungsspezifität
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Internal Region
    Reaktivität
    • 29
    • 15
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 28
    • 1
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 14
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CASZ1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
    Hersteller Produkt- Nr.
    600-401-b62
    Hersteller
    Rockland
    Verwendungszweck
    CASZ1 Antibody
    Kreuzreaktivität (Details)
    This affinity purified antibody is directed against human CASZ1 protein.
    Produktmerkmale
    Synonyms: rabbit anti-CASZ1 Antibody, CASZ1, Zinc finger protein castor homolog 1, Castor-related protein, Zinc finger protein 693, CST, SRG, ZNF693
    Aufreinigung
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of Human Casz1 protein.

    Immunogen Type: Conjugated Peptide

    Isotyp
    IgG
  • Applikationshinweise

    Immunohistochemistry Dilution: User Optimized

    Application Note: This antibody has been tested for use in ELISA, IHC, IF, and western blotting. This antiserum detects endogenous CASZ1 proteins, both the hCASZ5 and hCASZ11 isoforms. Expect a band approximately 125 kDa for hCASZ5 and 190 kDa for hCASZ11 in size corresponding CASZ1 by western blotting in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:1,000 - 1:5,000

    ELISA Dilution: 1:45,000

    IF Microscopy Dilution: User Optimized

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.09 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Lunde, Okaty, Dymecki, Glover: "Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups." in: eNeuro, Vol. 6, Issue 1, (2019) (PubMed).

    Zhang, Bonasio, Strino, Kluger, Holloway, Modzelewski, Cohen, Reinberg: "SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors." in: Genes & development, Vol. 27, Issue 7, pp. 749-66, (2013) (PubMed).

  • Target
    CASZ1 (Castor Zinc Finger 1 (CASZ1))
    Andere Bezeichnung
    CASZ1 (CASZ1 Produkte)
    Hintergrund
    Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. The human castor zinc finger 1 gene (CASZ1) regulates the production of the castor transcription factor, having increased expression when cells of neural and mesenchymal origin are induced to differentiation. CASZ1 is expressed in a number of human tumors and it localizes to a genomic region frequently lost in tumors of neuroectodermal origin. The CASZ1 gene generates 2 mRNA isoforms hCASZ5 and hCASZ11 that could encode proteins containing 5 or 11 zinc finger motifs, respectively. The proteins may be especially labile. Expect a band at 125 kDa for hCASZ5 and 190 kDa for hCASZ11 in fresh lysates.
    Gen-ID
    54897, 145207289
    UniProt
    Q86V15
Sie sind hier:
Kundenservice