YBX3/DBPA Antikörper

Produktnummer ABIN964622

Produktdetails anti-YBX3/DBPA Antikörper

Target: YBX3/DBPA (YBX3) (Y Box Binding Protein 3 (YBX3))

Reaktivität: Borrelia burgdorferi

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YBX3/DBPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Lateral Flow (LF)

Spezifität: This product was Protein-A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography. This antibody is specific for Borrelia burgdorferi DbpA protein. A BLAST analysis was used to suggest cross-reactivity with DbpA from Borrelia burgdorferi sources based on 100% homology with the immunizing sequence. Partial reactivity is expected against Borrelia garinii sources based on 60-80% homology. Cross-reactivity with DbpA from other sources has not been determined.

Produktmerkmale: This product is antibody made against DbpA, or Decorin Binding Protein A from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. DbpA from other microbial organisms such as E. coli (ATP-dependent RNA helicase DbpA) are significantly different. The spirochete migrates from the tick midgut during tick feeding to tick salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix, enabling bacteria to colonize in mammalian tissues. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host.

Immunogen: MBP-fusion protein corresponding to Borrelia burgdorferi Dbp-A protein.
Immunogen Type: RecombinantProtein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: This protein-A purified antibody has been tested for use in Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 18.5 kDa in size corresponding to Borrelia burgdorferi DbpA protein by Western blotting in the appropriate cell lysate or extract.

Kommentare:

Gene Name: dbpA, BB_A24

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL

Konzentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Haltbarkeit: 12 months

Details zu YBX3/DBPA

Target: YBX3/DBPA (YBX3) (Y Box Binding Protein 3 (YBX3))

Andere Bezeichnung: DBP A (YBX3 Produkte)

Synonyme: CSDA antikoerper, CSDA1 antikoerper, DBPA antikoerper, ZONAB antikoerper, csda antikoerper, Csda antikoerper, Dpba antikoerper, MSY3 antikoerper, MSY4 antikoerper, Yb2 antikoerper, dbpA antikoerper, oxyR antikoerper, Dbpa antikoerper, Y-box binding protein 3 antikoerper, Y-box binding protein 3 S homeolog antikoerper, Y box protein 3 antikoerper, Y box binding protein 3 antikoerper, YBX3 antikoerper, ybx3.S antikoerper, Ybx3 antikoerper

Hintergrund: This product is antibody made against DbpA, or Decorin Binding Protein A from the spirochete Borrelia burgdorferi, which is carried by Ixodes ticks. DbpA from other microbial organisms such as E. coli (ATP-dependent RNA helicase DbpA) are significantly different. The spirochete migrates from the tick midgut during tick feeding to tick salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix, enabling bacteria to colonize in mammalian tissues. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host.
Synonyms: Decorin-binding Protein A, Borrelia burgdorferi dbpA

Gen-ID: 1194347

NCBI Accession: NP_045697

UniProt: O50917