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IL-6 Antikörper

Rockland 209-301-310 IL6 Reaktivität: Human WB, ELISA, FACS, MA Wirt: Maus Monoclonal 33A12-G9 unconjugated
Rockland
Produktnummer ABIN964743
Hersteller Produkt- Nr.: 209-301-310
  • Target Alle IL-6 (IL6) Antikörper anzeigen
    IL-6 (IL6) (Interleukin 6 (IL6))
    Reaktivität
    • 193
    • 129
    • 75
    • 25
    • 21
    • 21
    • 14
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    Human
    Wirt
    • 194
    • 88
    • 68
    • 16
    • 4
    • 3
    • 2
    Maus
    Klonalität
    • 216
    • 156
    • 1
    Monoklonal
    Konjugat
    • 201
    • 58
    • 27
    • 12
    • 11
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-6 Antikörper ist unkonjugiert
    Applikation
    • 265
    • 135
    • 100
    • 57
    • 52
    • 47
    • 41
    • 41
    • 37
    • 31
    • 25
    • 25
    • 20
    • 19
    • 16
    • 10
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Multiplex Assay (MA)
    Hersteller Produkt- Nr.
    209-301-310
    Hersteller
    Rockland
    Verwendungszweck
    IL-6 Antibody
    Kreuzreaktivität (Details)
    This purified antibody detects recombinant and native IL-6 present in body fluids and cell supernatants in various assays (ie.IL-1 stimulated IL-6 production from fibroblasts).
    Produktmerkmale
    Synonyms: mouse Anti-IL-6 antibody, mouse anti-interleukin-6 antibody, HSF, Hybridoma growth factor, Hybridoma plasmacytoma growth factor, IFNB2, IL 6, IL6 protein, Interferon beta 2, Interleukin 6, BSF2, CDF
    Aufreinigung
    Protein A purified
    Sterilität
    Sterile filtered
    Endotoxin-Niveau
    Low Endotoxin
    Immunogen

    Immunogen: This Protein A purified IL-6 monoclonal antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-6 produced in E.coli followed by hybridoma development.

    Immunogen Type: Recombinant Protein

    Klon
    33A12-G9
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL6 Primärantikörper
  • Applikationshinweise

    Flow Cytometry Dilution: 0.5 mg/mL

    Application Note: Anti-IL-6 antibody has been tested for use in ELISA, Flow Cytometry, and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/μl by the LAL method. By western blot a band approximately 23.7 kDa in size corresponding to native human IL-6 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.

    Western Blot Dilution: 1:1000

    ELISA Dilution: 1:10,000

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2.19 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store IL 6 antibody at -20° C . For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Target
    IL-6 (IL6) (Interleukin 6 (IL6))
    Andere Bezeichnung
    IL6 (IL6 Produkte)
    Hintergrund
    Background: IL-6 is a secreted cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. IL-6 induces myeloma and plasmacytoma growth and induces nerve cells differentiation and acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. IL-6 also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. Anti-IL-6 antibody is ideal for investigators involved in Cancer, Neuroscience and Immunology research.
    Gen-ID
    3569
    NCBI Accession
    NP_000591
    UniProt
    P05231
    Pathways
    TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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