POLB Antikörper (C-Term)
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- Target Alle POLB Antikörper anzeigen
- POLB (Polymerase (DNA Directed), beta (POLB))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser POLB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Hersteller Produkt- Nr.
- 600-401-c65
- Hersteller
- Rockland
- Verwendungszweck
- POLB Antibody
- Kreuzreaktivität (Details)
- This antibody reacts with overexpressed and endogenous POLß protein.
- Produktmerkmale
- Synonyms: rabbit anti-POLB antibody, rabbit anti-DNA polymerase beta antibody, DNA polymerase ß, POLß, POL-B, POL-ß, pol-beta, beta-pol
- Aufreinigung
- This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.
- Sterilität
- Sterile filtered
- Immunogen
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Immunogen: This affinity-purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the C-terminus of the POLß protein.
Immunogen Type: Conjugated Peptide
- Isotyp
- IgG
- Top Product
- Discover our top product POLB Primärantikörper
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- Applikationshinweise
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Application Note: This affinity purified POLß antibody has been tested by ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 38.1 kDa in size corresponding to POLß by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 0.5 μg/mL
ELISA Dilution: 1:50,000
Other: User Optimized
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.4 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- Haltbarkeit
- 12 months
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- Target
- POLB (Polymerase (DNA Directed), beta (POLB))
- Andere Bezeichnung
- POLB (POLB Produkte)
- Hintergrund
- Background: The POLß protein belongs to the DNA polymerase type-X family. It is a DNA polymerase involved in gap-filling DNA synthesis or base excision and repair in a stepwise distributive fashion unlike other DNA polymerases. It is required for DNA maintenance, replication, recombination, and drug resistance. It is normally found as a monomer, in the cytoplasm and it translocates to the nucleus upon DNA damage.
- Gen-ID
- 5423
- NCBI Accession
- NP_002681
- UniProt
- P06746
- Pathways
- DNA Reparatur
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