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ABL2 Antikörper

ABL2 Reaktivität: Human, Maus WB, ELISA, IF Wirt: Maus Monoclonal 1H1 unconjugated
Produktnummer ABIN965499
  • Target Alle ABL2 Antikörper anzeigen
    ABL2
    Reaktivität
    • 78
    • 26
    • 24
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 87
    • 7
    Maus
    Klonalität
    • 80
    • 14
    Monoklonal
    Konjugat
    • 28
    • 9
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ABL2 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 41
    • 26
    • 26
    • 12
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of ABL2 expressed in E. Coli.
    Klon
    1H1
    Isotyp
    IgG1
    Top Product
    Discover our top product ABL2 Primärantikörper
  • Applikationshinweise
    Western Bloting: 1/500 - 1/2000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    ABL2
    Andere Bezeichnung
    ABL2 (ABL2 Produkte)
    Synonyme
    ABLL antikoerper, ARG antikoerper, Abll antikoerper, Arg antikoerper, AA536808 antikoerper, ABL proto-oncogene 2, non-receptor tyrosine kinase antikoerper, v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene) antikoerper, ABL2 antikoerper, Abl2 antikoerper
    Hintergrund
    ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.
    Synonyms: ARG, ABLL, FLJ22224, FLJ31718, FLJ41441
    Molekulargewicht
    128kDa
    Gen-ID
    27
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