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AKT3 Antikörper
AKT3
Reaktivität: Human
WB, ELISA
Monoclonal
unconjugated
Produktdetails anti-AKT3 Antikörper
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Target
Alle AKT3 Antikörper anzeigen
AKT3
(V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
Reaktivität
Alle Reaktivitäten für AKT3 Antikörper
Human
Wirt
Bitte anfragen
Klonalität
Alle Klonalitäten für AKT3 Antikörper
Monoklonal
Konjugat
Alle Konjugate für AKT3 Antikörper
Dieser AKT3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für AKT3 Antikörper
Western Blotting (WB), ELISA
Spezifität
Ni-NTA purified truncated recombinant Akt3 expressed in E. Coli strain BL21 (DE3)
Aufreinigung
Crude ascites.
Top Product
Discover our top product AKT3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Western Blot: 1: 500- 1: 2000 ELISA: Propose dilution 1: 10,000. Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Lagerung
-20 °C
Referenzen für anti-AKT3 Antikörper (ABIN965532)
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Easton, Cho, Roovers, Shineman, Mizrahi, Forman, Lee, Szabolcs, de Jong, Oltersdorf, Ludwig, Efstratiadis, Birnbaum : "Role for Akt3/protein kinase Bgamma in attainment of normal brain size. " in: Molecular and cellular biology , Vol. 25 , Issue 5 , pp. 1869-78 , (2005 ) (PubMed ).
Stahl, Sharma, Cheung, Zimmerman, Cheng, Bosenberg, Kester, Sandirasegarane, Robertson : "Deregulated Akt3 activity promotes development of malignant melanoma. " in: Cancer research , Vol. 64 , Issue 19 , pp. 7002-10 , (2004 ) (PubMed ).
Details zu AKT3
(ausblenden)
Target
AKT3
(V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
Andere Bezeichnung
Akt3 (AKT3 Produkte )
Synonyme
MPPH antikoerper, PKB-GAMMA antikoerper, PKBG antikoerper, PRKBG antikoerper, RAC-PK-gamma antikoerper, RAC-gamma antikoerper, STK-2 antikoerper, AI851531 antikoerper, D930002M15Rik antikoerper, Nmf350 antikoerper, Pkbg antikoerper, AKT serine/threonine kinase 3 antikoerper, thymoma viral proto-oncogene 3 antikoerper, v-akt murine thymoma viral oncogene homolog 3b antikoerper, AKT3 antikoerper, Akt3 antikoerper, akt3b antikoerper
Hintergrund
Akt3 (also designated protein kinase B gamma or vakt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
Gen-ID
10000
Pathways
PI3K-Akt Signalweg , RTK Signalweg , TLR Signalweg , Hepatitis C , VEGF Signaling
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