ALDH1L1 Antikörper (C-Term)

Produktnummer ABIN965537

Produktdetails anti-ALDH1L1 Antikörper

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH1L1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse ALDH1L1(Aldehyde dehydrogenase 1 family member L1)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ALDH1L1 Antikörper (ABIN965537)

Krupenko, Wagner: "Aspartate 142 is involved in both hydrolase and dehydrogenase catalytic centers of 10-formyltetrahydrofolate dehydrogenase." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35777-84, (2000) (PubMed).

Case, Kaisaki, Steele: "Resolution of rat liver 10-formyltetrahydrofolate dehydrogenase/hydrolase activities." in: The Journal of biological chemistry, Vol. 263, Issue 21, pp. 10204-7, (1988) (PubMed).

Details zu ALDH1L1

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Andere Bezeichnung: ALDH1L1 (ALDH1L1 Produkte)

Synonyme: 10-FTHFDH antikoerper, 10-fTHF antikoerper, FDH antikoerper, FTHFD antikoerper, Fthfd antikoerper, 1810048F20Rik antikoerper, Neut2 antikoerper, fthfd antikoerper, ALDH1L1 antikoerper, DKFZp469C068 antikoerper, aldehyde dehydrogenase 1 family member L1 antikoerper, aldehyde dehydrogenase 1 family, member L1 antikoerper, cytosolic 10-formyltetrahydrofolate dehydrogenase antikoerper, aldehyde dehydrogenase 1 family member L1 L homeolog antikoerper, ALDH1L1 antikoerper, Aldh1l1 antikoerper, aldh1l1 antikoerper, LOC476506 antikoerper, LOC100465263 antikoerper, aldh1l1.L antikoerper

Hintergrund: ALDH1L1 ((Aldehyde dehydrogenase 1 family member L1) converts 10-formyltetrahydrofolate, a precursor for nucleotide biosynthesis, to tetrahydrofolate. The protein comprises two functional domains: a hydrolase domain that removes a formyl group from 10-formyltetrahydrofolate and a NADP(+)-dependent dehydrogenase domain that reduces the formyl to carbon dioxide. It is localized in cytoplasm and contains 1 acyl carrier domain. In the N-terminal section, it belongs to the GART family. In the C-terminal section, it belongs to the aldehyde dehydrogenase family.