ARHGEF15 Antikörper (C-Term)

Produktnummer ABIN965590

Produktdetails anti-ARHGEF15 Antikörper

Target: ARHGEF15 (rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF15 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ARHGEF15 (Rho guanine nucleotide exchange factor 15)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ARHGEF15

Target: ARHGEF15 (rho Guanine Nucleotide Exchange Factor (GEF) 15 (ARHGEF15))

Andere Bezeichnung: ARHGEF15 (ARHGEF15 Produkte)

Hintergrund: ARHGEF15(Rho guanine nucleotide exchange factor 15) is a specific GEF for RhoA activation and the regulation of vascular smooth muscle contractility. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. ARHGEF15 functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells.