ARL1 Antikörper (N-Term)

Produktnummer ABIN965592

Produktdetails anti-ARL1 Antikörper

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ARL1(ADP-ribosylation factor-like protein 1)

Anwendungsinformationen

Applikationshinweise: ELISA, Western blotting: 1µg/ml for 2hrs.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Referenzen für anti-ARL1 Antikörper (ABIN965592)

Van Valkenburgh, Shern, Sharer, Zhu, Kahn: "ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22826-37, (2001) (PubMed).

Hong, Lee, Patton, Lin, Moss, Vaughan: "Phospholipid- and GTP-dependent activation of cholera toxin and phospholipase D by human ADP-ribosylation factor-like protein 1 (HARL1)." in: The Journal of biological chemistry, Vol. 273, Issue 25, pp. 15872-6, (1998) (PubMed).

Details zu ARL1

Target: ARL1 (ADP Ribosylation Factor Like GTPase 1 (ARL1))

Andere Bezeichnung: ARL1 (ARL1 Produkte)

Synonyme: ARFL1 antikoerper, 2310008D22Rik antikoerper, AU019749 antikoerper, zgc:92883 antikoerper, 72CDd antikoerper, ARL1 antikoerper, ARL1_DROME antikoerper, Arf antikoerper, Arf72A antikoerper, BcDNA:GM20805 antikoerper, CG 6025 antikoerper, CG6025 antikoerper, Dmel\CG6025 antikoerper, P25160 antikoerper, arf72A antikoerper, arf[72A] antikoerper, arl antikoerper, arl1 antikoerper, dARL1p antikoerper, dArl1 antikoerper, l(3)72Ae antikoerper, l(3)72CDd antikoerper, arfl1 antikoerper, ADP ribosylation factor like GTPase 1 antikoerper, ADP-ribosylation factor like GTPase 1 antikoerper, ADP-ribosylation factor-like 1 antikoerper, ADP-ribosylation factor-like protein 1 antikoerper, ADP ribosylation factor-like 1 antikoerper, ADP ribosylation factor like GTPase 1 L homeolog antikoerper, ARL1 antikoerper, Arl1 antikoerper, arl-1 antikoerper, arl1 antikoerper, arl1.L antikoerper

Hintergrund: ARL1(ADP-ribosylation factor-like protein 1) belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Recent data show that Arl1 regulates the membrane recruitment of Golgin-97, which plays a role in transport from the endosome to the trans-Golgi network.