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BLK Antikörper

BLK Reaktivität: Human WB, ELISA, IHC Monoclonal unconjugated
Produktnummer ABIN965674
  • Target Alle BLK Antikörper anzeigen
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Reaktivität
    • 66
    • 24
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    Bitte anfragen
    Klonalität
    • 56
    • 10
    Monoklonal
    Konjugat
    • 35
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BLK Antikörper ist unkonjugiert
    Applikation
    • 50
    • 37
    • 28
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3)
    Aufreinigung
    Crude ascites.
    Isotyp
    IgG1
    Top Product
    Discover our top product BLK Primärantikörper
  • Applikationshinweise
    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    IHC(F): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Lagerung
    -20 °C
  • Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." in: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).

  • Target
    BLK (B Lymphoid Tyrosine Kinase (BLK))
    Andere Bezeichnung
    BLK (BLK Produkte)
    Synonyme
    bltk antikoerper, si:dkey-33i22.2 antikoerper, zgc:136231 antikoerper, MODY11 antikoerper, BLK proto-oncogene, Src family tyrosine kinase antikoerper, B lymphoid kinase antikoerper, blk antikoerper, BLK antikoerper, Blk antikoerper
    Hintergrund
    BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src nonreceptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
    Gen-ID
    640
    Pathways
    Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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