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ChT Antikörper (C-Term)

ChT Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965895
  • Target Alle ChT Antikörper anzeigen
    ChT (High Affinity Choline Transporter (ChT))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 9
    • 9
    • 8
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 9
    • 8
    Kaninchen
    Klonalität
    • 9
    • 8
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    Dieser ChT Antikörper ist unkonjugiert
    Applikation
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human choline transporter
    Top Product
    Discover our top product ChT Primärantikörper
  • Applikationshinweise
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Apparsundaram, Ferguson, George, Blakely: "Molecular cloning of a human, hemicholinium-3-sensitive choline transporter." in: Biochemical and biophysical research communications, Vol. 276, Issue 3, pp. 862-7, (2000) (PubMed).

  • Target
    ChT (High Affinity Choline Transporter (ChT))
    Andere Bezeichnung
    CHT1 (ChT Produkte)
    Synonyme
    CHT antikoerper, CHT1 antikoerper, HMN7A antikoerper, hCHT antikoerper, Cht1 antikoerper, solute carrier family 5 member 7 antikoerper, solute carrier family 5 (choline transporter), member 7 antikoerper, SLC5A7 antikoerper, Slc5a7 antikoerper
    Hintergrund
    The choline transporter is a hemicholinium-3-sensitive phosphorylated transmembrane protein, the protein regulates high-affinity choline uptake, and plays the roles in disease states. CHT1(High-affinity choline transporter 1) imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. CHT1 is sodium ionand chloride ion-dependent. CHT1 is expressed in putamen, spinal cord and medulla and is specific for cholinergic neurons. CHT1 is specifically inhibited by nanomolar concentrations of hemicholinium 3. CHT1 belongs to the sodium: solute symporter (SSF) (TC 2.A.21) family.
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