CTCF Antikörper
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- Target Alle CTCF Antikörper anzeigen
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
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Reaktivität
- Human, Affe
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CTCF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CTCF expressed in E. Coli.
- Klon
- 1D11
- Isotyp
- IgG1
- Top Product
- Discover our top product CTCF Primärantikörper
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- Applikationshinweise
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
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Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." in: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).
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Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." in: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).
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- Target
- CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
- Andere Bezeichnung
- CTCF (CTCF Produkte)
- Synonyme
- im:7152666 antikoerper, CTCF antikoerper, xctcf antikoerper, AW108038 antikoerper, CCCTC-binding factor antikoerper, CCCTC-binding factor (zinc finger protein) antikoerper, CTCF antikoerper, ctcf antikoerper, Ctcf antikoerper
- Hintergrund
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This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.
Tissue specificity: Ubiquitous. Absent in primary spermatocytes.
Synonyms: CTCF - Molekulargewicht
- 83kDa
- Gen-ID
- 10664
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